Title: The costs of functional gastrointestinal disorders and related signs and symptoms in infants: a systematic literature review and cost calculation for England
| Authors: | James Mahon, Carlos Lifschitz, Thomas Ludwig, Nikhil Thapar, Julie Glanville, Mohamad Miqdady, Miguel Saps, Seng Hock Quak, Irene Lenoir Wijnkoop, Mary Edwards, Hannah Wood, Hania Szajewska |
| Published: | November 1, 2017 |
| Journal: | BMJ Journal |
About 1 in every 2 infants experiences at least one FGID (functional gastrointestinal disorder) or its related symptoms within the first year after birth. The most common FGIDs in infants are regurgitation, infantile colic, and functional constipation.
Treatment algorithms have been developed for the management of FGIDs, with parental support, reassurance and nutritional advice recommended in the first line. However, some infants are being medicated unnecessarily, which suggests a discrepancy between treatment recommendations and their implementation. This results in substantial expenses incurred by third-party payers and parents.
Researchers from UK, Argentina, USA, United Arab Emirates, Poland, The Netherlands and Singapore conducted a study by using England as an example to calculate the potential costs of treating FGIDs in infants to third-party payers and to parents. FGID-treatment related data from 2014-2015 were collected from publicly available sources.
The study found that the annual total cost of treating FGIDs in infants was estimated to be at least £72.3 million. £49.1 million was attributed to health system expenditures and £23.2 million to parents through the purchase of over-the-counter remedies and anti-regurgitation formulas.
This is the first study on the costs of regurgitation, infantile colic, and constipation in infants. The high number of healthcare professional consultations and over-the-counter remedy purchases indicate the stress of parents.
The study also demonstrates a discrepancy between treatment guidelines – which emphasize the value of parental reassurance and nutritional advice – and their implementation.
For more details about the study, please read the full text of the paper.
Citation: Mahon J, Lifschitz C, Ludwig T, Thapar N, Glanville J, Miqdady M, Saps M, Quak SH, Wijnkoop IL, Edwards M, Wood H, Szajewska H. The costs of functional gastrointestinal disorders and related signs and symptoms in infants: a systematic literature review and cost calculation for England. BMJ Open 2017;7:e015594. doi: 10.1136/bmjopen-2016-015594